Citation

Shintani-Ishida K, Idota N, Tsuboi H, Tsurumi R, Ikegaya H. Leg. Med. (Elsevier) 2022; 59: 102149.

Copyright

(Copyright © 2022, Japanese Society of Legal Medicine, Publisher Elsevier Publishing)

DOI

10.1016/j.legalmed.2022.102149

PMID

36166973

Abstract

Suicides by pentobarbital overdose have increased since about 2012, which appear to be influenced by technical information on active euthanasia that has spread over the Internet. We encountered a pentobarbital poisoning case of a patient with amyotrophic lateral sclerosis. A caregiver found the patient unconscious immediately after two visitors left the room. The patient was immediately transferred to the emergency hospital but eventually declared dead. A fatal concentration of pentobarbital was detected in peripheral blood samples collected in the emergency hospital and during autopsy (53.8 μg/mL and 29.4 μg/mL, respectively). Because the ratios of pentobarbital concentrations between the gastric contents and peripheral blood were 35 and 29 in the hospital and autopsy samples, respectively, it is likely that pentobarbital was administered via the gastrostomy tube. The patient had contacted the visitors through social media. Although the patient had requested the doctor perform active euthanasia and expressed a desire to end their life on social media, nobody had noticed the plan to commit suicide.

Language: en

Keywords

Humans; Poisoning; *Suicide; Barbiturates; Pentobarbital; Active euthanasia; *Drug Overdose; Gastrointestinal Contents; Gastrostomy tube; Internet suicide