Citation

Anani-mekle S. Journal Europeen des Urgences et de Reanimation 2022; 34(1): 39-44.

Copyright

(Copyright © 2022)

DOI

10.1016/j.jeurea.2022.02.003

PMID

unavailable

Abstract

The toxic effect of duloxetine and quétiapine poisoning appears within the six hours after ingestion in the clinic studies. We report the case of a 55-year-old man who ingested between 1.6 g and 2.4 g of duloxetine, 1 g of quétiapine and alcohol for the suicide attempt. Signs of overdose occur 15 hours after ingestion. It is mainly duloxetine poisoning. The patient presents a coma, a tachycardia without QT abnormality, an arterial hypotension requiring resuscitation. He recovery completely 48 hours after ingestion. This case report suggests that an overdose with the reported doses requires clinical monitoring of at least fifteen hours. The mechanism behind the delay in the onset of signs of intoxication is not known. © 2022 Elsevier Masson SAS

Language: en

Keywords

adult; human; male; alcohol; resuscitation; case report; suicide attempt; drug overdose; clinical article; drug intoxication; tachycardia; quetiapine; middle aged; coma; QT interval; hypotension; duloxetine; Article; Toxic effects; Delay onset; Signs of overdose; Voluntary poisoning