Citation

Karabulut S. Noro Psikiyatr Ars 2022; 59(3): 232-236.

Copyright

(Copyright © 2022, Turk Noro-Psikiyatri Derneginin Yayin Organidir)

DOI

10.29399/npa.27965

PMID

unavailable

Abstract

INTRODUCTION: In this study, it was aimed to screen inpatients in the Antalya Ataturk State Hospital Alcohol and Substance Addiction Treatment Center (AMATEM) Clinic in terms of anti-hepatitis C virus (anti-HCV) seropositivity and to compare them in terms of sociodemographic data and clinical characteristics.

METHOD: The files of inpatients in the AMATEM Clinic of Ataturk State Hospital between July 2020 - February 2021 were retrospectively scanned and recorded with a semi-structured data form. The collected data was analysed using the SPSS 26.0 program. Independent sample t-test was used for normally distributed numerical variables, Mann-Whitney U test was used for non-normally distributed numerical variables, and chi-square test was used for categorical variables. To examine the relationship between variables showing significant difference and Anti-HCV positivity, binary logistic regression analysis was used. The limit of statistical significance was accepted as p<0.05 for all analyses.

RESULTS: Of the 155 patients included in the study, 57.4% were diagnosed with opiate use disorder, 40% with multiple substance use disorder. The rate of multiple substance use, syringe use, syringe sharing, self-mutilation and tattoo/piercing were significantly higher in anti-HCV positive patients (p=0.02, p<0.001, p<0.001, p=0.02, p=0.03 respectively). Patients who were positive for anti-HCV had been using substances for a longer time and were hospitalized more frequently, and the Addiction Profile Index substance abuse subscale scores were higher (p<0.001, p=0.001, p=0.01, respectively).

CONCLUSION: The risk of exposure to HCV in patients with substance use disorder is significantly higher than non-substance user population. It is important to perform anti-HCV screening, especially for people who inject drugs to prevent under-diagnosis of the disease. Considering the risk posed by the use and sharing of syringes, it seems necessary to develop preventive and therapeutic approaches meticulously. © 2021 by Turkish Association of Neuropsychiatry.

Language: en

Keywords

adult; human; female; male; alcohol; alcoholism; schizophrenia; anxiety; substance use; suicide attempt; Addiction; risk factor; major clinical study; controlled study; retrospective study; automutilation; opiate; statistical significance; demography; hepatitis C; disease duration; tobacco dependence; Article; rank sum test; Mini Mental State Examination; medication compliance; sensation seeking; needle sharing; substance; underdiagnosis