Citation

Freeman E, Adair M, Beeler D, Casper R, Herman MP, Reeves D, Reinsch S. Cephalalgia Reports 2022; 5.

Copyright

(Copyright © 2022)

DOI

10.1177/25158163221096866

PMID

unavailable

Abstract

OBJECTIVES: To qualitatively identify evidence-based literature related to the daily burden and unmet treatment and psychosocial needs of patients with cluster headache (CH).

METHODS: A literature search was conducted through October 20, 2020 across MEDLINE, EMBASE, CINAHL, and PsychInfo databases exploring quality of life (QoL) and disease burden in adults with CH. The search was restricted to full-text reports in peer-reviewed journals.

METHODologic quality was assessed using the Critical Skills Appraisal Program.

RESULTS: From 11 identified publications, QoL was reduced in persons living with CH, with significant psychological, social, and socio-economic burdens, and work-related disability. The CH disease trajectory is complex, with patients experiencing the impact of their disease across multiple domains beyond the biological manifestation of the disease including stigma, employment limitations, and suicidal ideation, and with a lack of effective treatment from the patient perspective.

DISCUSSION: These findings strengthen comprehension of the CH patient experience, enabling a deeper understanding of the patients' perspective and experience of their disease andunmet needs, providing a basis for future research into this debilitating condition. Minor limitations of this study include data extraction and study selection biases. © The Author(s) 2022.

Language: en

Keywords

adult; disability; human; cognition; social interaction; suicide; systematic review; female; male; Review; quality of life; herbal medicine; family; ketamine; cannabis; suicidal ideation; caffeine; quality control; qualitative research; occupation; cocaine; emotion regulation; migraine; mental disease; comprehension; disease association; data base; clinical feature; automutilation; human relation; headache; health service; opiate; leisure; vitamin; health care cost; patient attitude; employment; social status; health economics; productivity; psychosocial care; daily life activity; diagnostic error; peer review; prospective study; lysergide; health care utilization; absenteeism; health care system; psychedelic agent; melatonin; medical leave; employment status; evidence based practice; cluster headache; family relation; clinical assessment; work capacity; patient identification; data extraction; tension headache; X ray; semi structured interview; thematic analysis; working time; delayed diagnosis; n,n dimethyltryptamine; tryptamine derivative; taurine; holistic care; multicenter study (topic); social stigma; disease burden; illness trajectory; midomafetamine; psilocybine; energy drink; unmet medical need; chronic cluster headache; patient insights; primary headache; primary headache disorder