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Citation |
Brendan Montano C, Jackson WC, Vanacore D, Weisler RH. Neuropsychiatr. Dis. Treat. 2022; 18: 867-879. |
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Copyright |
(Copyright © 2022, Dove Press) |
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DOI |
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PMID |
unavailable |
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Abstract |
Primary care clinicians have a vital role to play in the diagnosis and management of patients with major depressive disorder (MDD). This includes screening for MDD as well as identifying other possible psychiatric disorders including bipolar disorder and/or other comorbidities. Once MDD is confirmed, partnering with patients in the shared decision-making process while considering different treatment options and best management of MDD over the course of their illness is recommended. Vortioxetine has been approved for the treatment of adults with MDD since 2013, and subsequent US label updates indicate that vortioxetine may be particularly beneficial for specific populations of patients with MDD, including those with treatment-emergent sexual dysfunction and patients experiencing certain cognitive symptoms. Given these recent label updates, this prescribing guide for vortioxetine aims to provide clear and practical guidance for primary care clinicians on the safe and effective use of vortioxetine for the treatment of MDD, including how to identify appropriate patients for treatment. © 2022 Montano et al. Language: en |
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Keywords |
memory; human; age; suicide; Review; patient safety; drug use; major depression; antidepressant; Edinburgh Postnatal Depression Scale; primary medical care; vomiting; prescription; sexual dysfunction; patient monitoring; practice guideline; constipation; drug safety; learning disorder; drug efficacy; risk benefit analysis; drug tolerability; nausea; health care management; screening test; relapse; maintenance therapy; clinical decision making; drug dose regimen; Hospital Anxiety and Depression Scale; patient identification; Geriatric Depression Scale; Patient Health Questionnaire 9; Mood Disorder Questionnaire; behavior assessment; vortioxetine; patient risk; clinician; Columbia suicide severity rating scale; shared decision making; processing speed; measurement-guided care; Rapid Mood Screener; shared decision-making; treatment emergent sexual dysfunction |