CONTACT US: Contact info
|
Citation |
Farahani MV, Soltani S, Marashi SM. Int. J. Med. Toxicol. Forensic Med. 2022; 12(2). |
|
Copyright |
(Copyright © 2022, Department of Forensic Medicine, Shahid Beheshti University of Medical Sciences) |
|
DOI |
|
PMID |
unavailable |
|
Abstract |
Nitroglycerin, a vasodilator, is commonly administered to treat ischemic heart disease. Adverse effects after toxicity are light-headedness, nausea, blurry vision, and syncope due to low systolic blood pressure as well as methemoglobinemia. A 19-year-old female was admitted to our toxicology department after suicidal ingestion of 320 mg extended-release nitroglycerin about 45 minutes before the admission. She was conscious, and her initial blood pressure was 98/65 mm Hg, which was decreased to 77 mmHg within 1.5 hours despite administration of 1 liter of normal saline. Due to severe hypotension, norepinephrine infusion was started for systolic blood pressure maintenance above 80mm Hg; however, she started complaining of palpitation and chest pain. So, the dose of norepinephrine was reduced, and glucose, insulin, and potassium protocol were started. After 3 hours of therapy, her hemodynamic condition stabilized with systolic blood pressure above 90mm Hg; hence norepinephrine was discontinued. She was discharged on the 3rd day after the psychiatric consultation, with regular clinical and paraclinical examinations. © 2022 Shahid Beheshti University of Medical Sciences. All rights reserved. Language: en |
|
Keywords |
adult; human; female; case report; suicide attempt; consultation; clinical article; drug intoxication; hospital admission; psychologic assessment; noradrenalin; activated carbon; ingestion; fluid therapy; hemodynamics; hypotension; glyceryl trinitrate; sodium chloride; consciousness; glucose; electrocardiogram; Toxicity; potassium; metabolic acidosis; Hypotension; heart palpitation; thorax pain; oxygen saturation; drug dose reduction; Article; blood gas analysis; systolic blood pressure; drug dose increase; young adult; T wave inversion; alkalosis; pig insulin; Hyperinsulinemic euglycemia; Nitroglycerin |