Citation

Kim K, Jeon HJ, Myung W, Suh SW, Seong SJ, Hwang JY, Ryu JI, Park SC. J. Pers. Med. 2022; 12(3).

Copyright

(Copyright © 2022, MDPI: Multidisciplinary Digital Publishing Institute)

DOI

10.3390/jpm12030381

PMID

unavailable

Abstract

Psychosis can include schizophrenia, mood disorders with psychotic features, delusional disorder, active delirium, and neurodegenerative disorders accompanied by various psychotic symptoms. Late-onset psychosis requires careful intervention due to the greater associated risks of secondary psychosis; higher morbidity and mortality rates than early-onset psychosis; and complicated treatment considerations due to the higher incidence of adverse effects, even with the black box warning against antipsychotics. Pharmacological treatment, including antipsychotics, should be carefully initiated with the lowest dosage for short-term efficacy and monitoring of adverse side effects. Further research involving larger samples, more trials with different countries working in consortia, and unified operational definitions for diagnosis will help elaborate the clinical characteristics of late-onset psychosis and lead to the development of treatment approaches. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Language: en

Keywords

Review; incidence; dementia; traumatic brain injury; exercise; schizophrenia; mortality; suicide attempt; mood disorder; mild cognitive impairment; psychoeducation; morbidity; mental health care; neuroleptic agent; differential diagnosis; socioeconomics; psychologic assessment; tricyclic antidepressant agent; degenerative disease; hallucination; nuclear magnetic resonance imaging; electroconvulsive therapy; Alzheimer disease; intervention study; electrolyte disturbance; caregiver; risperidone; computer assisted tomography; delirium; cholinergic receptor blocking agent; depressive psychosis; schizoaffective psychosis; Management; electrocardiography; cyanocobalamin; hypochondriasis; kidney function; delusional disorder; apolipoprotein E; brain damage; liver function; serotonin noradrenalin reuptake inhibitor; paliperidone; cognitive behavioral therapy; behavior assessment; late onset psychosis; Late-onset schizophrenia-like psychosis; molecular epidemiology; psychological therapy; Secondary psychosis