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Citation |
Jiang B, Li Y, Hu H, Cai W, Li X. Chinese Journal of Psychiatry 2022; 55(4): 319-322. |
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Copyright |
(Copyright © 2022) |
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DOI |
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PMID |
unavailable |
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Abstract |
Anorexia nervosa (AN) is a type of eating disorder characterized by severe malnutrition and abnormally low body weights, resulting from patients′ intentionally strict restrictions on eating. Patients with AN often have body image disturbances and are comorbid with psychiatric symptoms, such as obsessive‑compulsive symptoms, depression, anxiety, and so forth. These patients may suffer from severe malnutrition, amenorrhea, and even death since they refuse to eat. As a mental disorder with a high mortality rate, there is still no specific medicine to treat AN. This case is a female patient with AN treated with bilateral anterior capsulotomy (BACA) combined with deep brain stimulation (DBS). The treatment efficacy was evident. Before the operation, her body mass index (BMI) was only 12.22 kg/m2. She had repeated binge‑eating‑emetic behaviors, severe obsessive‑compulsive symptoms, anxiety and depression, suicide attempt, severe malnutrition, amenorrhea, recurrent infections, and so forth. At the 3‑month follow‑up after the operation, the patient was emotionally stable and had a BMI of 19.40 kg/m2. The reducing rates of the total scores of the Hamilton Anxiety Scale (HAMA), the 24‑item Hamilton Depression Scale (HAMD24), and the Yale‑Brown Obsessive‑Compulsive Scale (Y‑BROW) were 64%, 64%, and 52%, respectively. This study found that BACA combined with DBS surgery can rapidly and effectively improve the prognosis of patients with the binge‑eating/purging subtype of AN. © 2022 Chinese Medical Journals Publishing House Co.Ltd. All Rights Reserved. Language: zh |
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Keywords |
human; female; case report; depression; malnutrition; suicide attempt; anorexia nervosa; disease severity; Anorexia nervosa; clinical article; priority journal; anxiety disorder; follow up; obsessive compulsive disorder; brain depth stimulation; capsulotomy; Article; amenorrhea; Deep brain stimulation; recurrent infection; Hamilton Anxiety Scale; Yale Brown Obsessive Compulsive Scale; Hamilton Depression Rating Scale; Bilateral anterior capsulotomy |