Citation

Porto CM, Barbosa Da Silva NS, Porto Lira CM, Magalhães RP, Magalhães JLO, Santana Da Silva TP, Sougey EB. Curr. Psychiatry Res. Rev. 2022; 18(1): 60-69.

Copyright

(Copyright © 2022)

DOI

10.2174/2666082217666211122155401

PMID

unavailable

Abstract

BACKGROUND: One of the risk factors for suicide includes the presence of depressive disorder and symptoms, which may be related to the reduction of 25-hydroxyvitamin D serum levels. In this scenario, evidence shows vitamin D deficiency as an important aspect directly related to depressive disorder chronicity.

OBJECTIVE: To assess the association between Vitamin D serum levels and the intensity of depressive symptoms and suicidal behavior in a clinical sample of depressed patients.

METHODS: A cross-sectional study with 146 patients aged between 18 and 59, seen in two psychiatry ambulatories. Data collection involved measurement of serum 25-hydroxyvitamin D levels and assessment of the intensity of depressive symptoms and suicide risk.

RESULTS: In the sample, 35% presented low Vitamin D serum levels and, in these individuals, the incidence of family history of Depressive Disorder (95.2%) and chronicity of severe depressive symptoms (47.8%) was higher. As to suicidal behavior, both groups presented high active suicide risk, with higher rates in the group with hypovitaminosis D. Only suicidal ideation was linked to lower Vitamin D levels (67.4% p= 0,005).

CONCLUSION: In this study, hypovitaminosis D was associated with negative mental health outcomes, such as more severe chronicity of depressive symptoms and suicidal behavior, characterized by active suicidal ideation. © 2022 Bentham Science Publishers.

Language: en

Keywords

adult; Behavior; human; Suicide; female; male; Psychiatry; lethality; suicidal ideation; depression; Depressive symptoms; Major depressive disorder; Suicide risk; major depression; suicidal behavior; risk assessment; disease severity; Attempted; risk factor; vitamin D deficiency; major clinical study; mental disease; questionnaire; cross-sectional study; disease duration; Montgomery Asberg Depression Rating Scale; Article; semi structured interview; Vitamin D; sociodemographics; Columbia suicide severity rating scale; 25 hydroxyvitamin D; Vitamin D deficiency