Citation

Badu AB, Cempakadewi AA, Budihardja BM, Ake A. Eur. J. Case Rep. Intern. Med. 2022; 9(1).

Copyright

(Copyright © 2022, SMC Media)

DOI

10.12890/2022_003126

PMID

unavailable

Abstract

Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy intoxication, especially in healthcare facilities without access to haemodialysis. A patient had attempted suicide by ingesting 2,4-D dimethylamine, with toxic effects on the central and peripheral nervous systems, and the gastrointestinal and respiratory systems. However, she significantly improved after alkaline diuresis, accompanied by resuscitation, decontamination of the gastrointestinal system, and supportive therapies. © EFIM 2022.

Language: en

Keywords

adult; human; suicide; female; resuscitation; case report; abdominal pain; hemodialysis; vomiting; clinical article; drug intoxication; intensive care unit; herbicide; brain edema; paracetamol; sepsis; hypotension; urinalysis; sodium chloride; dexamethasone; bicarbonate; Glasgow coma scale; potassium; gastrointestinal tract; respiratory alkalosis; infusion fluid; leukocytosis; malaise; furosemide; burning sensation; oxygen saturation; drug dose reduction; Article; omeprazole; blood gas analysis; hypokalemia; ondansetron; septic shock; cefotaxime; loading drug dose; flow cytometry; young adult; breathing rate; hypertensive factor; neutrophilia; 2,4 dichlorophenoxyacetic acid; medical procedures; decontamination; tranexamic acid; 2,4-D dimethylamine; alkaline diuresis; Alkaline diuresis; blood clot lysis; Chlorophenoxy; Herbicide intoxication