Citation

Yang L, Li HF, Bai YC, Ju RH, Yu XZ, Yu WB, Wen K, Shen JZ, Wang ZH. Journal of Instrumental Analysis 2021; 40(4): 495-502.

Copyright

(Copyright © 2021)

DOI

10.3969/j.issn.1004-4957.2021.04.009

PMID

unavailable

Abstract

Rodenticides are the most economical and effective way to control rodents. Meanwhile, most rodenticides have a strong toxicity to human or livestock. The abuse of rodenticides not only poses a risk to non-target animals, but also threatens human beings. Numerous human poisoning events occur via accidental exposure, secondary poisoning, suicide attempts and malicious poisonings. As rodenticides poisoning is a serious public health problem, it is urgent and necessary to establish reliable and rapid methods for poisoning diagnosis and rodenticides analysis. Establishing the preclinical detection of rodenticides poisoning, especially the rapid detection methods, are very critical to determine the treatment and rescue measures. The current analyses of rodenticides are mainly dependent on the instrumental methods, including liquid chromatography - mass spectrometry ( LC - MS ) and gas chromatography ( GC ). Recently, immunoassay has been used in the rapid detection of rodenticides due to its simple fabrication and operation low-cost and portability. The advances in poisonings of fluoroacetamide, tetramethylenedisulfotetramine and anticoagulant rodenticides aswelas their detection methods are summarized in this paper which is anticipated to provide a technical in-struction for researchers in the corelative fields. © 2021, China Association for Instrumental Analysis. All rights reserved.

Language: zh

Keywords

review; immunoassay; instrumental analysis; rodenticides