Citation

Alibeigi M, Mousavi-Roknabadi RS, Goli NA, Sharifi M, Farahmand F. Int. J. Med. Toxicol. Forensic Med. 2021; 11(4).

Copyright

(Copyright © 2021, Department of Forensic Medicine, Shahid Beheshti University of Medical Sciences)

DOI

10.32598/ijmtfm.v11i4.34976

PMID

unavailable

Abstract

BACKGROUND: The suicide with aluminum phosphide, known as rice tablet, has increased significantly. This study aimed to investigate the epidemiology of Aluminum Phosphide (ALP) poisoning and determine the in-hospital mortality prognostic factors in adult people referring to ALP poisoning to one of the main poisoning centers in southern Iran.

METHODS: This retrospective cross-sectional study (March 21, 2014, to March 21, 2018) was conducted on all adult patients (>16 years) with ALP poisoning who were referred to Ali-Asghar Hospital (affiliated with Shiraz University of Medical Sciences). All data were extracted from the patients' medical files. The patients were categorized into two groups of survived and non-survived. Univariate and multivariate logistic regression analyses were conducted to determine prognostic factors for in-hospital mortality, and Odds Ratios (ORs) were reported.

RESULTS: Totally, 97 patients were enrolled in this study. The patients' Mean±SD age was 29.3±12.2 years. Both study groups (survived and non-survived) were matched in most demographic and poisoning characteristics. Nausea (62.9%) and vomiting (49.5%) were the most symptoms at the time of admission. Castor oil (66%), N-acetyl cysteine (56.7%), and magnesium sulfate (52.6%) were the most frequent treatment in these patients. The multivariate analysis showed that age (OR=1.12, 95%CI: 1.03-1.22), body temperature (OR=0.02, 95%CI: 0.01-0.48), resistant acidosis (OR=77.10, 95%CI: 5.05-1176.86), and taking sodium bicarbonate (OR=12.35, 95%CI: 1.25-122.10) were the prognostic factors of in-hospital mortality.

CONCLUSION: The in-hospital mortality rate in patients with ALP poisoning was 29.9%. Age, illiteracy, body temperature, resistant acidosis, and taking sodium bicarbonate were the prognostic factors of in-hospital mortality in these patients. © 2021 Shahid Beheshti University of Medical Sciences. All rights reserved.

Language: en

Keywords

adolescent; adult; human; naloxone; female; male; Poisoning; prognosis; Iran; aged; Prevalence; depression; prevalence; suicide attempt; docosahexaenoic acid; aluminum phosphide; comorbidity; intoxication; major clinical study; urban area; vomiting; retrospective study; hydrocortisone; length of stay; epidemiological data; middle aged; intensive care unit; groups by age; noradrenalin; dopamine; poison center; survivor; cross-sectional study; nausea; hypotension; acute kidney failure; atropine; dexamethasone; acetylcysteine; bicarbonate; dobutamine; gluconate calcium; magnesium sulfate; body temperature; Aluminum phosphide; ascorbic acid; Article; alpha tocopherol; ondansetron; acidosis; young adult; liver protective agent; mortality rate; epinephrine; illiteracy; castor oil; hydroxyethyl starch; in-hospital mortality; livergol; Prognostic factor