Citation

Arafat SMY, Karim AKMB, Hossain MF, Menon V, Shoib S. Health Sci. Rep. 2021; 4(3).

Copyright

(Copyright © 2021, John Wiley and Sons)

DOI

10.1002/hsr2.347

PMID

unavailable

Abstract

BACKGROUND: Precise identification of risk factors for suicide has been found as fundamentally challenging for the stakeholders. In search of that, the determination of potential biological markers of suicide has been scrutinizing in recent days. However, replicative studies across the culture and time are warranted to utilize the biomarkers in decision-making while considering suicide prevention.

OBJECTIVES: We aimed to measure the neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) in non-fatal suicidal attempts.

METHODS: This cross-sectional study was conducted from August 2020 to May 2021. Data were collected from 26 hospitalized patients after an immediate non-fatal suicidal attempt. We collected blood samples and assessed the complete blood count, NLR, and CRP. Data were analyzed by Statistical Package for the Social Science version 24.0 and Microsoft Excel software. We performed the independent Mann-Whitney U test to determine the variations between the groups. A value <.05 was considered as the level of significance.

RESULTS: The mean age of the study population was 24.1 (±7.3), more than half of them (n = 19, 73.1%) were female. The mode of attempt was either hanging (n = 13, 50.0%) or poisoning (n = 13, 50.0%). The previous attempt was noted in 12 (46.2%) cases. The mean CRP level was 16.8 (±30.2) mg/L and the mean NLR level was 8.3 (±6.8) for the total sample. Both the CRP and NLR were significantly higher among those who attempted hanging (P =.019 and.001).

CONCLUSIONS: The current study revealed preliminary findings on CRP and NLR among non-fatal suicides in Bangladesh where both of the parameters were significantly higher in non-fatal hanging. © 2021 The Authors. Health Science Reports published by Wiley Periodicals LLC.

Language: en

Keywords

adult; human; sexual abuse; female; male; Bangladesh; decision making; pilot study; suicide attempt; C reactive protein; inflammation; risk factor; C-reactive protein; controlled study; blood sampling; clinical article; hospital admission; automutilation; intensive care unit; hospital patient; follow up; cross-sectional study; lymphocytopenia; leukocyte count; protein expression; leukocytosis; body mass; Article; blood cell count; biological marker; hematological parameters; neutrophil; neutrophilia; comorbidity assessment; nervous system inflammation; neutrophil lymphocyte ratio; cross-sectional analysis; neutrophil-to-lymphocyte ratio; non-fatal suicidal attempts; suicide in Bangladesh