Citation

Sobolevskaia PA, Andreev BV, Churilov LP, Fedotkina TV, Gilburd B, Stanova AK, Utekhin VJ, Shoenfeld Y. Dubai Medical Journal 2021; 4(4): 317-319.

Copyright

(Copyright © 2021)

DOI

10.1159/000518554

PMID

unavailable

Abstract

A kind of autoimmune encephalitis with positive autoantibodies toward the B1 subunit of the gamma-aminobutyric acid-type B receptor is known as anti-GABABR encephalitis. It is an autoimmune brain disorder with typical manifestations of a limbic encephalitis. It can coexist with positive anti-thyroid autoantibodies. We described a 57-year-old woman who was diagnosed with a bipolar affective disorder. The patient had high titers of anti-thyroid peroxidase antibodies, and she also was positive for anti-GABABR antibodies. There is a question, if this case is a kind of comorbidity of anti-thyroid and anti-brain autoimmunity or is it a single nosological entity- A kind of Hashimoto's encephalopathy? © 2021 The Author(s). Published by S. Karger AG, Basel.

Language: en

Keywords

adult; human; female; brain; case report; bipolar disorder; suicide attempt; comorbidity; disease classification; anxiolytic agent; clinical article; prolactin; prolactin blood level; human tissue; clomipramine; unclassified drug; quetiapine; middle aged; psychopharmacotherapy; thyrotropin; thyrotropin blood level; carbamazepine; olanzapine; Psychiatric disorders; Bipolar affective disorder; liothyronine; thyroxine; Article; thyroxine blood level; recommended drug dose; Hashimoto disease; antibody; antibody blood level; 4 aminobutyric acid B receptor; 4 aminobutyric acid B receptor antibody; Autoimmunity; Hashimoto's thyroiditis; immunofluorescence assay