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Citation |
More DB, Malve H, Wankhede MN. Toxicol. Int. 2021; 28(4): 403-409. |
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Copyright |
(Copyright © 2021, Society of Toxicology India) |
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DOI |
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PMID |
unavailable |
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Abstract |
A usual ingredient of rodenticide, aluminium phosphide is known for its poisoning which happens to be one of the common causes of suicides in India. Signs and symptoms of toxicity with aluminium phosphide are wellknown. Circulatory failure plays an important role in mortality with aluminium phosphide poisoning. Aluminium phosphide poisoning is associated with high mortality as there is no specific antidote available yet. There is a need for correct treatment approach to manage this fatal poisoning. In this retrospective analysis we present a data of forty cases registered at a tertiary care hospital in Mumbai. We developed a multidisciplinary treatment approach to aluminium phosphide poisoning which may help in better patient outcomes. Correct treatment protocol with supportive therapy resulted in better survival in these patients. Hence we propose this aggressive, appropriate management with continuous haemodynamic monitoring and multidisciplinary treatment approach to reduce the mortality in aluminium phosphide poisoning. © 2021 Informatics Publishing Limited and The Society of Toxicology. All rights reserved. Language: en |
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Keywords |
adult; human; female; male; mortality; aluminum phosphide; treatment outcome; controlled study; retrospective study; clinical article; tachycardia; dopamine; emergency ward; hypotension; high school; amiodarone; artificial ventilation; antibiotic agent; dobutamine; magnesium sulfate; educational status; sinus tachycardia; respiratory distress; Article; aluminum overload; heart left ventricle ejection fraction; sinus bradycardia; cardiogenic shock; complete heart block; atrioventricular junction arrhythmia; mortality rate; tertiary care center; left ventricular systolic dysfunction; multidisciplinary team; Aluminium Phosphide Toxicity; hemodynamic monitoring; Multidisciplinary Treatment; Rodenticide Poisoning |