Citation

Shirk DV, Williams SD. Curr. Psychiatry Res. Rev. 2020; 16(4): 288-291.

Copyright

(Copyright © 2020)

DOI

10.2174/2666082216999201126165311

PMID

unavailable

Abstract

BACKGROUND: Ehlers-Danlos Syndromes (EDS) comprise a group of heterogeneous hereditary connective tissue disorders [1, 2]. Psychiatric disorders such as depression, anxiety, panic disorder, agoraphobia, schizophrenia, neurodevelopmental disorders, personality disorder, eating disorders, substance misuse and interpersonal issues have been reported in the literature to be associated with EDS [1-3].

OBJECTIVES: The case of a 15-year old male who was hospitalized after a suicide attempt by gunshot, who was discovered to have symptoms suggestive of EDS, is presented in this paper along with the results of a literature search of psychiatric manifestations of EDS in children and adolescents.

METHODS: Literature review was conducted on the UpToDate website on March 11, 2020 to review symptoms of Ehlers-Danlos Syndrome for the purpose of preliminary diagnosis of this patient. Ad-ditional literature search was conducted on PubMed on 4/2/20 at 12:10 P.M. and on 4/9/20 at 10:51 P.M. and on the search engine Google on 4/2/20 at 12:25 P.M. On May 11, 2020 at 2 P.M., another web search was conducted with a review of 6 different websites pertaining to Ehlers-Danlos Syndrome.

RESULTS: A systematic review of psychiatric manifestations of Ehlers-Danlos Syndromes revealed a strong incidence of psychiatric symptoms.

CONCLUSION: Our patient's psychiatric symptoms of depression, suicidal ideations, anxiety and social and educational struggles may have been at least partially due to chronic pain-abdominal, headache and musculoskeletal, and social ostracization associated with Ehlers-Danlos Syndrome. Education regarding this illness helped our patient's recovery as he came to understand why he was so "odd" and the cause of his multisystemic chronic pain. © 2020 Bentham Science Publishers.

Language: en

Keywords

adolescent; human; Depression; systematic review; male; case report; quality of life; bipolar disorder; psychotherapy; abdominal pain; psychiatry; suicidal ideation; depression; schizophrenia; anxiety; psychosis; chronic pain; suicide attempt; personality; hospitalization; Anorexia; posttraumatic stress disorder; migraine; anorexia; mental disease; personality disorder; sexual behavior; clinical article; headache; duloxetine; heredity; Article; sumatriptan succinate; oppositional defiant disorder; musculoskeletal pain; loss of appetite; kyphoscoliosis; Abdominal pain; Ehlers Danlos syndrome; Hereditary; Joint hypermobility; Migraines; Musculoskeletal pain