Citation

Hasse-Sousa M, Martins DS, Petry-Perin C, Arrial-Cordeiro RT, Rabelo-da-Ponte FD, Rosa AR, Bücker J, Gama CS, Czepielewski LS. Eur. J. Psychiatry 2020; 34(3): 153-159.

Copyright

(Copyright © 2020, Departmento de Psiquiatria de la Facultad de Medicina de Zaragoza)

DOI

10.1016/j.ejpsy.2020.04.003

PMID

unavailable

Abstract

Background and objectives: Individuals with bipolar disorder have an elevated risk of suicide. One hypothesis is that deficits in inhibitory control may play a significant part in suicidal behavior. However, the relationship between inhibitory control and suicide behavior in bipolar disorder is still unclear. This study aims, therefore, to investigate the effects of inhibitory control with other clinical variables on the likelihood that individuals with bipolar disorder have had previous suicide attempts.

METHODS: 96 euthymic individuals with bipolar disorder were recruited and underwent a clinical interview. Inhibitory control was measured through the Stroop Color-Word Test. A logistic regression model was conducted to investigate the effects of multiple hospitalizations, age of disease diagnosis, family history of severe mental disorders, sex and inhibitory control performance, controlling for age and estimated intellectual functioning.

RESULTS: The model revealed statistically significant main effects of multiple hospitalizations, female sex and family history of psychiatric disorders. Unexpectedly, inhibitory control performance was not a significant predictor, even after designing a new model excluding the clinical variables.

CONCLUSIONS: Current inhibitory control performance was not related to the likelihood of previous suicide attempts in individuals with BD, reinforcing the evidence of major effects of clinical risk factors. It may play an indirect role in suicidal behavior, however, as it may be related to greater illness severity, which, in turn, may be related to more severe episodes and increased suicidal behavior. © 2020 Asociación Universitaria de Zaragoza para el Progreso de la Psiquiatría y la Salud Mental

Language: en

Keywords

adult; human; Suicide; female; male; Cognition; bipolar disorder; Bipolar disorder; sex difference; suicide attempt; interview; hospitalization; major clinical study; mental disease; controlled study; disease association; middle aged; family history; cross-sectional study; Article; inhibition (psychology); Stroop test; Inhibitory control