Citation

Bellefroid C, Goffin P, Guntz J, Deville M. Case Rep. Crit. Care 2020; 2020.

Copyright

(Copyright © 2020, Hindawi Publishing)

DOI

10.1155/2020/6962591

PMID

unavailable

Abstract

Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution. © 2020 Céline Bellefroid et al.

Language: en

Keywords

adult; human; female; shock; case report; abdominal pain; suicide attempt; drug overdose; clinical article; hospital admission; priority journal; intensive care unit; noradrenalin; hypotension; anamnesis; glucose blood level; non insulin dependent diabetes mellitus; lactic acidosis; metformin; Article; tachypnea; continuous hemodiafiltration; young adult; arterial pH; anticoagulation