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Citation |
Park SC, Kim K, Jang OJ, Kim SG, Lee JG, Park JH, Choi J, Lee DW, Lin SK, Tan CH, Shinfuku N, Park YC. Psychiatry Investig. 2019; 16(6): 459-463. |
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Copyright |
(Copyright © 2019, Korean Neuropsychiatric Association) |
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DOI |
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PMID |
unavailable |
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Abstract |
Our study aimed to analyze the clinical characteristics and psychotropic prescription patterns of a history of suicide attempts in South Koreans with bipolar disorder (BD), by using only Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar disorder. The patterns of clinical characteristics and psychotropic drug use were compared among 53 patients with a history of suicide attempts and 297 without this history; the potential effects of confounding variables were adjusted with binary logistic analyses for discrete variables and analyses of covariance for continuous variables. After adjusting the effects of age, sex, duration of illness, and enrollment as an outpatient, patients with a history of suicide attempts were characterized by a significantly more prevalent depressive episode, lower prevalent remission state, lower levels of hemoglobin, and more use of antidepressants, anxiolytics, and hypnotics compared to those without lifetime suicide attempt. The inability to plan goal-directed behavior may be an intervening factor in the relationship between suicide attempts and depression in BD. Relatively low hemoglobin levels can be associated with manic episodes in patients with a history of suicide attempts and the use of antidepressants, anxiolytics, or hypnotics can be associated with suicide attempts in BD patients. © 2019 Korean Neuropsychiatric Association. Language: en |
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Keywords |
adult; human; age; female; male; bipolar disorder; Bipolar disorder; psychotherapy; depression; prevalence; Suicide attempt; education; drug use; suicide attempt; Korea; Antidepressant; major clinical study; seasonal variation; prescription; antidepressant agent; antiparkinson agent; anxiolytic agent; neuroleptic agent; triacylglycerol; clinical feature; middle aged; cholesterol; mania; hypnotic agent; hypnosis; remission; tranquilizing activity; disease duration; mood stabilizer; body mass; Article; employment status; hemoglobin; blood cell count; rapid cycling bipolar disorder; mixed mania and depression; Hemoglobin; Depressive episode; antidepressant activity; platelet count |