Citation

Lin-ming LUO, Shi-feng CHU, Yi-na JIANG, Piao LUO, Nai-hong CHEN. Yao Xue Xue Bao 2017; (12): 510-516.

Copyright

(Copyright © 2017, Zhongguo yao xue hui)

DOI

unavailable

PMID

unavailable

Abstract

Neural stem cells (NSCs) posse the specialty of tumor tropism and be able to migrate specifically to tumor cells. NSCs are also cross the blood brain barrier. NSCs keep in touch with tumor cells preferentially under the tumor microenvironment, and surround the target cells. Based on these characteristics, NSCs can be used as a carrier for therapeutic virus, enzymes/prodrugs, genes or suicide genes, etc. which are selectively delivered to the glioma cells. NSCs may be modified by a variety of different genes to establish a reliable, safe and effective therapy for glioma.

Language: zh

Keywords

carrier; glioma; neural stem cell; targeted therapy; tumor tropism