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Journal Article

Citation

Jollant F, Olié E. Douleur analg 2018; 31(3): 122-128.

Copyright

(Copyright © 2018)

DOI

10.3166/dea-2018-0013

PMID

unavailable

Abstract

Psychological pain is part of the human experience. However, it sometimes takes on a pathological character-by its intensity, its duration, or the associated cognitive processes-that in particular increases the risk of suicidal ideation and acting out. Its definition remains the subject of debate. Several scales have also been developed to improve its measurement. Recent studies, in particular, neuroimaging in the social context, suggest the involvement of a cerebral network, including the anterior cingulate cortex and the anterior insula, which partially overlaps the circuits of physical pain. In addition, the opioid system could play a role in modulating psychological pain. Recent work also points to the inflammatory system in a bidirectional relationship with psychological pain. Social pain, a particular form of psychological pain, could represent an alarm system during the threat of social disconnection, a process threatening the survival of the individual. Recently, several preliminary studies awaiting replication suggest pathways for specific treatment of psychological pain, including buprenorphine, paracetamol, or brain stimulation. © 2018 Springer-Verlag France. All rights reserved.


Language: fr

Keywords

human; Suicide; survival; Opioids; social isolation; inflammation; neuroimaging; psychological aspect; paracetamol; social environment; Paracetamol; neuropathic pain; brain depth stimulation; Article; buprenorphine; Scale; opiate receptor; psychological pain; anterior cingulate; Cortex; anterior insula

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