Citation

von Oertzen TJ. Zeitschrift fur Epileptologie 2018; 31(1): 28-33.

Copyright

(Copyright © 2018)

DOI

10.1007/s10309-017-0149-7

PMID

unavailable

Abstract

Depression next to anxiety is the most common comorbidity in epilepsy. Depression in people with epilepsy (PwE) reduces quality of life and increases suicide risk especially in the first year after diagnosis of epilepsy. Depression causes an increase in seizure frequency. Depression in PwE is often missed. Screening tools increase the detection rate for depression in this patient group. The underlying mechanism of this comorbidity is still debated. Therapeutic options include optimizing anticonvulsive drugs, antidepressants particularly selective reuptake inhibitors, cognitive behavioral therapy, and in drug refractory epilepsy vagal nerve stimulation. Data on the effects of those therapies are sparse and clinical studies in this patient group are urgently needed. © 2017, Springer Medizin Verlag GmbH.

Language: de

Keywords

Questionnaires; human; Depression; suicide; Epilepsy; Review; Comorbidity; quality of life; Antidepressive agents; depression; comorbidity; risk factor; epilepsy; anticonvulsive agent; antidepressant agent; serotonin uptake inhibitor; seizure; screening test; vagus nerve stimulation; cognitive behavioral therapy; drug resistant epilepsy