Citation

Kulacaoglu F, Kose S. Brain Sci. 2018; 8(11).

Copyright

(Copyright © 2018, Switzerland Molecular Diversity Preservation International (MDPI) AG)

DOI

10.3390/brainsci8110201

PMID

unavailable

Abstract

Borderline personality disorder (BPD) is a chronic psychiatric disorder characterized by pervasive affective instability, self-image disturbances, impulsivity, marked suicidality, and unstable interpersonal relationships as the core dimensions of psychopathology underlying the disorder. Across a wide range of situations, BPD causes significant impairments. Patients with BPD suffer considerable morbidity and mortality compared with other populations. Although BPD is more widely studied than any other personality disorder, it is not understood sufficiently. This paper briefly reviews the recent evidence on the prevalence, etiology, comorbidity, and treatment approaches of borderline personality disorder (BPD) by examining published studies, and aims to offer a more coherent framework for the understanding and management of borderline personality disorder. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.

Language: en

Keywords

human; sexual abuse; Review; Comorbidity; Treatment; prevalence; mortality; suicide attempt; Borderline personality disorder; lithium; comorbidity; posttraumatic stress disorder; neuroimaging; pathogenesis; morbidity; automutilation; impulsiveness; Etiology; borderline state; irritability; valproic acid; lamotrigine; topiramate; attention deficit disorder; maternal care; serotonin 2A receptor; oxytocin; DSM-5; anterior cingulate; endophenotype