Citation

Morita S, Taniguchi G, Tamune H, Kumakura Y, Kondo S, Kasai K. Epilepsy Behav. Case Rep. 2018; 10: 102-105.

Copyright

(Copyright © 2018, Elsevier Publishing)

DOI

10.1016/j.ebcr.2018.07.007

PMID

unavailable

Abstract

Depressive disorders in epilepsy often present characteristic clinical manifestations atypical in primary, endogenous depression. Here, we report a case of a 64-year-old woman with right mesial temporal lobe epilepsy, who complained of bizarre, antipsychotic-refractory cenesthetic hallucinations in her interictal phase, and was hospitalized after a suicide attempt. Detailed clinical observations revealed mood symptoms, which led to the diagnosis of interictal dysphoric disorder comorbid with interictal psychosis. Sertraline with low-dose aripiprazole markedly alleviated both depressive and psychotic symptoms. This case suggested that the two diagnostic entities may overlap and that depressive symptoms tend to be concurrent when concurring with psychosis, which hampers the appropriate choice of a treatment option. © 2018 The Authors

Language: en

Keywords

adult; human; female; case report; depression; anxiety; psychosis; suicide attempt; hospitalization; treatment outcome; comorbidity; mood disorder; clinical article; sertraline; priority journal; hallucination; middle aged; nuclear magnetic resonance imaging; daily life activity; carbamazepine; risperidone; drug withdrawal; dysphoria; Sertraline; lamotrigine; phenytoin; clinical observation; clonazepam; low drug dose; Interictal dysphoric disorder; electroencephalography; Aripiprazole; aripiprazole; Article; drug dose increase; drug substitution; Temporal lobe epilepsy; abnormal sensation; hippocampal sclerosis; Japanese (people); interictal dysphoric disorder; cenesthopathy; housekeeping; Interictal depression; interictal psychosis; Interictal psychosis; mesial temporal lobe epilepsy; perospirone; shoulder disease; single photon emission computed tomography