Citation

Direk MC, Yildirim V, Günes S, Bozlu G, Okuyaz C. Clin. Psychopharmacol. Neurosci. 2016; 14(4): 388-390.

Copyright

(Copyright © 2016, Korean College of Neuropsychopharmacology)

DOI

10.9758/cpn.2016.14.4.388

PMID

unavailable

Abstract

Serotonin syndrome (SS) is a potentially life-threatening condition associated with increased serotonergic activity in central nervous system and may occur during the use of serotonergic drugs. Although increasing frequency of serotonergic drug use in children, pediatricians, emergency medicine and pediatric intensive care specialists have not enough knowledge and experience about SS that is a potentially life-threatening condition. A 12-year-old girl patient was admitted to our emergency room with the history of involuntary contractions on her extremities and alteration of consciousness. Her physical examination showed agitation, hyperthermia, dilated pupils, tremor, increased deep tendon reflexes, positive spontaneous clonus, agitation, flushed skin and diaphoresis, excessive perspiration, and continuous horizontal ocular movements. The patient diagnosed as SS by clinical history, physical and laboratory findings. In this paper, we will discuss SS occurred in a 12-year-old girl after concurrent clomipramine and risperidone use. Copyright © 2016, Korean College of Neuropsychopharmacology.

Language: en

Keywords

Child; human; child; female; case report; suicide attempt; serotonin; school child; hospital admission; clomipramine; automutilation; physical examination; emergency ward; risperidone; tremor; serotonin syndrome; agitation; creatine kinase; diaphoresis; epileptic state; Risperidone; Serotonin syndrome; flushing; Article; hyperthermia; consciousness disorder; hydration; mydriasis; medical history; tendon reflex; Early diagnosis; creatine kinase blood level; involuntary movement; clonus; myoglobin; Clomipramine; habit; reflex disorder; pediatric intensive care unit; repeat procedure