Citation

Reiter E, Heim B, Scherfler C, Mueller C, Nocker M, Ndayisaba JP, Loescher W, Seppi K, Lees AJ, Warner T, Poewe W, Wenning GK, Djamshidian A. Mov. Disord. Clin. Pract. (Hoboken) 2016; 3(4): 382-388.

Copyright

(Copyright © 2016, John Wiley and Sons)

DOI

10.1002/mdc3.12301

PMID

unavailable

Abstract

BACKGROUND: Cerebral hemiatrophy syndromes can present with variable neurological symptoms. In childhood epilepsy, mental retardation and neuropsychiatric disorders are common while in adults movement disorders, such as highly asymmetric parkinsonism or hemidystonia as well as neuropsychiatric problems have been reported.

METHODS: Here, we present three adult patients with features that expand the clinical spectrum and give an overview of the most common clinical signs associated with this rare condition.

RESULTS: All three patients had prominent neuropsychiatric symptoms such as mood swings and increased irritability. Furthermore, one patient developed hemichorea which can be a rare presentation of cerebral hemiatrophy.

CONCLUSIONS: Cerebral hemiatrophy syndromes are a heterogeneous group of disorders that may also present with neuropsychiatric symptoms or hemichorea. © 2016 International Parkinson and Movement Disorder Society

Language: en

Keywords

adult; human; female; male; case report; suicide attempt; polypharmacy; fatigue; pathological gambling; priority journal; quetiapine; middle aged; nuclear magnetic resonance imaging; risperidone; irritability; topiramate; apathy; dopaminergic transmission; amisulpride; parkinsonism; clonazepam; rigidity; levodopa; brain atrophy; epileptic state; anhedonia; glucose metabolism; neurologic examination; dysarthria; muscle atrophy; basal ganglion; Article; single drug dose; mood change; Mini Mental State Examination; dopamine transporter; continuous infusion; ropinirole; tiapride; electromyography; bradykinesia; bedtime dosage; apomorphine; chorea; nerve conduction; facial nerve paralysis; hemisphere; face asymmetry; synkinesis; cerebral hemiatrophy syndrome; emission tomography; fluorodeoxyglucose; hemichorea; imaging; neuropsychiatric symptoms; upper limb