Citation

Leban V, Brvar M. Farmacevtski Vestnik 2015; 66(4): 306-312.

Copyright

(Copyright © 2015)

DOI

unavailable

PMID

unavailable

Abstract

Drug intoxications in Slovenia account for about twothirds of all intoxications in adult patients, mostly due to intentional ingestion in suicidal attempts. The most frequent intoxications are those by drugs for the nervous system (80 %). Anxiolytics, hypnotics, and sedatives, particularly benzodiazepines, represent 45 % of all medications ingested in suicidal purposes. They are followed by intoxications with antipsychotics, antidepressants, and drugs for the musculoskeletal system, primarily analgesics. The most frequently observed clinical feature of severe drug intoxications is a reduced level of consciousness. Treatment is primarily symptomatic, although some drug intoxications can be treated with specific antidotes. In order to treat drug intoxications successfully, we need to know their toxicokinetic and toxicodynamic features. To improve prevention and treatment of intoxications, we need information of all intoxication in Slovenia, which can only be achieved through regular reporting of intoxications to the Slovenian Register of Intoxications.

Language: sk

Keywords

human; Poisoning; Suicide attempt; suicide attempt; disease severity; Drugs; analgesic agent; antidepressant agent; anxiolytic agent; neuroleptic agent; drug intoxication; clinical feature; Slovenia; benzodiazepine derivative; antidote; toxicokinetics; hypnotic sedative agent; sedative agent; Article; consciousness level