Citation

Prasanth SS, Rajasekaran A. International Journal of Pharma and Bio Sciences 2015; 6(1): P749-P758.

Copyright

(Copyright © 2015)

DOI

unavailable

PMID

unavailable

Abstract

Cerberin (2-o-Acetyl neriifolin) is the principal cardiac glycoside present in seeds of Cerbera odollam. The seeds of Cerbera odollam are used as a poison for suicidal as well as homicidal purpose by people around the world. Its detection in body fluids is somewhat difficult. The present study aims to develop a simple Ultra Violet derivative spectroscopic method for the estimation of cerberin from rat plasma without previous chemical separation using fourth derivative of the zero-order absorption spectra and the integrated area of the peak (valley) ranging from wavelength 305.2 to 307.2 nm.

Language: en

Keywords

homicide; suicide; methanol; intoxication; controlled study; unclassified drug; nonhuman; blood level; rat; chemical structure; dilution; cardiac glycoside; Article; plant seed; Rattus; Apocynaceae; Cerbera odollam; Cerberin; cerberin; Derivative; Rat blood plasma; ultraviolet spectroscopy; UltraViolet spectroscopy