Citation

Limosin F. Ann. Med. Psychol. (Paris) 2014; 172(3): 234-237.

Copyright

(Copyright © 2014, Societe Medico-Psychologique, Publisher Elsevier Publishing)

DOI

10.1016/j.amp.2014.02.014

PMID

unavailable

Abstract

Regarding the burden of mental disorders in elderly patients, including morbidity and mortality, especially by suicide, and impairment of quality of life and functional autonomy, there is a need to take into account special health care needs of elderly persons. In bipolar disorders, lithium tends to be under-prescribed in elderly patients, while it is still a first line choice in guidelines. If it is true that there is a lack of controlled studies on effectiveness of lithium in elderly patients, available data from lithium side effects, especially on renal function, don't justify this under-utilization. Moreover, anti-inflammatory and neuroprotective effects of lithium may be of particular interest in ageing, in preventing and/or controlling the occurrence of some neurodegenerative process. © 2014 Elsevier Masson SAS.

Language: fr

Keywords

human; Prevalence; quality of life; bipolar disorder; Bipolar disorder; Elderly; Dementia; lithium; article; elderly care; drug choice; drug efficacy; health care need; drug response; kidney function; neuroprotection; antiinflammatory activity; Side effect; Lithium citrate