Citation

Çolak, Erdoǧan M, Baydin A, Afacan MA, Katı C, Duran L. Turk. J. Med. Sci. 2014; 44(2): 279-282.

Copyright

(Copyright © 2014, Scientific and Technical Research Council of Turkey)

DOI

10.3906/sag-1211-31

PMID

unavailable

Abstract

AIM: To evaluate the usefulness of plasma glucose and serum cholinesterase levels as predictors of organophosphate-induced intermediate syndrome.

MATERIALS AND METHODS: Seventy-one organophosphate poisoning patients who were admitted to our emergency department during a 4-year period were evaluated retrospectively. Four patients were excluded from the study due to a lack of medical records. Categorical variables were analyzed using the chi-square test and nonparametric variables were analyzed using the Mann-Whitney U test.

RESULTS: Thirty-five (52.2%) patients were male and 32(47.8%) were female. Patients had a mean age of 39.4 ± 15.9 years and 70.1% of the patients were married. Oral intake (68.7%) was the most common method of intoxication, and attempted suicide (67.2%) was the most common cause. Te most common organophosphates were methamidophos (20.8%), dichlorvos (19.4%), parathion (7.5%), and methyl parathion (7.5%). Fifty-seven (85%) patients were treated in the emergency observation unit and 10 (15%) patients were admitted to the intensive care unit. Eleven (16%) patients developed intermediate syndrome and had significantly lower levels of serum cholinesterase (P < 0.01) and higher blood glucose levels (P = 0.037).

CONCLUSION: Initial serum cholinesterase and glucose levels measured in the emergency department may be a useful marker in predicting organophosphate-induced intermediate syndrome. © TÜBİTAK.

Language: en

Keywords

Humans; Adult; analysis; Female; Male; adult; Intoxication; human; female; male; epidemiology; Retrospective Studies; Patient Admission; Suicide, Attempted; Turkey; Emergency Service, Hospital; suicide attempt; Organophosphate; article; major clinical study; vomiting; retrospective study; hospital admission; emergency ward; emergency health service; glucose blood level; muscle weakness; blood; glucose; cholinesterase; Intermediate syndrome; diaphragm paralysis; Oximes; Cholinesterase Reactivators; oxime; statistics and numerical data; chemically induced; Vomiting; Muscle Weakness; Blood Glucose; organophosphate poisoning; cholinesterase reactivator; Respiratory Paralysis; Cholinesterases; Hyperglycemia; Cholinesterase; Organophosphate Poisoning