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Journal Article

Citation

Parveen S, Javed MA. Pak. J. Med. Sci. Q. 2013; 29(6).

Copyright

(Copyright © 2013, Professional Medical Publications)

DOI

10.12669/pjms.296.4385

PMID

unavailable

Abstract

Stevens-Johnsons Syndrome (SJS) is an immune-complex-mediated hypersensitivity reaction and has been linked as an adverse side effects to many drugs. Lamotrigine, an anticonvulsive medication and also a commonly used mood stabiliser, can be associated with this adverse reaction. Although this has not been reported very commonly, SJS has high mortality and morbidity and requires careful attention as the use of Lamotrigine is increasing in clinical practice. We present a case where the patient developed Stevens - Johnson Syndrome three weeks after being started on Lamotrigine. The case is discussed for its relevance to the use of Lamotrigine which is currently prescribed very commonly in psychiatric practices.


Language: en

Keywords

adult; human; female; case report; depression; suicide attempt; C reactive protein; disease severity; Lamotrigine; article; antidepressant agent; anxiolytic agent; sertraline; anxiety disorder; follow up; hospital discharge; drug withdrawal; patient satisfaction; lamotrigine; face edema; conjunctivitis; buspirone; Stevens Johnson syndrome; treatment response; papule; drug dose increase; treatment duration; hand; epidermis; vesicular rash; lip disease; foot; swelling; oral mucosal disease; Hypersensitivity reaction; lip swelling; Stevens-Johnsons syndrome

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