Citation

Soares MS, Paiva WS, Guertzenstein EZ, Amorim RL, Bernardo LS, Pereira JF, Fonoff ET, Teixeira MJ. Neuropsychiatr. Dis. Treat. 2013; 9: 509-515.

Copyright

(Copyright © 2013, Dove Press)

DOI

10.2147/NDT.S35823

PMID

unavailable

Abstract

Following the early studies of moniz and lima, psychosurgery had considerable scientific credibility until the advent of modern antipsychotics in the mid 1950s. thereafter, psychosurgery was almost abandoned in large medical centers as a common treatment for schizophrenia, although is still used for some affective and anxiety disorders. we reviewed relevant papers cited in the medline/index medicus, cochrane, and scielo databases from 1930 to 2012. in our review of the literature, we show from recent studies that there are still many patients with schizophrenia who have serious deficits even after being treated with current noninvasive therapies. the value of psychosurgery remains controversial. there are no data available to support the use of stereotactic procedures for schizophrenia. well designed controlled trials are needed to establish the effectiveness of psychosurgery in patients with schizophrenia. © 2013 soares et al, publisher and licensee dove medical press ltd.

Language: en

Keywords

human; suicide; systematic review; prognosis; Treatment; Schizophrenia; subdural hematoma; schizophrenia; medical education; Brief Psychiatric Rating Scale; review; epilepsy; fatigue; aggressiveness; personality disorder; cognitive defect; headache; nuclear magnetic resonance imaging; confusion; personality test; weight gain; pathological anatomy; amnesia; brain hemorrhage; surgical technique; postoperative infection; surgical mortality; enuresis; postoperative complication; lethargy; capsulotomy; stereotaxic surgery; postoperative edema; muscle disease; outcome assessment; Wechsler Intelligence Scale; psychosurgery; Psychosurgery; hemiplegia; amygdaloidotomy; anterior capsulotomy; aptitude test; cingulectomy; limbic leucotomy; loss of initiative; sphincter disturbance; Stereotactic techniques; subcaudate tractotomy; transient mania