Citation

Ramdurg S. Sleep Biol. Rhythms 2012; 10(3): 244-246.

Copyright

(Copyright © 2012, Japanese Society of Sleep Research, Publisher John Wiley and Sons)

DOI

10.1111/j.1479-8425.2012.00534.x

PMID

unavailable

Abstract

Kleine-Levin syndrome (KLS) is an intriguing, severe, homogenous disease, with well defined clinical features, but no clear cause or treatment. Therefore studies on KLS were done exclusively with case report or series. There are limited systemic study comparing KLS with controls on phenomenology, cause, investigations and management. We report four cases of KLS presented to us along with core symptoms, hypomanic and catatonic features. Response to treatment also different with one case responded to lithium while others required combination of therapy. KLS is still evolving disorder having cluster of varying symptoms and response to treatment. This needs further exploration and higher studies © 2012 Sleep and Biological Rhythms © 2012 Japanese Society of Sleep Research.

Language: en

Keywords

adolescent; adult; human; mental health; suicide; male; case report; psychosis; food intake; lithium; mood disorder; article; antidepressant agent; neuroleptic agent; clinical feature; priority journal; somnolence; nuclear magnetic resonance imaging; sexual intercourse; olanzapine; lorazepam; irritability; defense mechanism; clinical examination; methylphenidate; antibiotic agent; electroencephalography; hypersomnia; mood stabilizer; Article; single photon emission computer tomography; hypersexuality; upper respiratory tract infection; antipyretic agent; mutism; hyperphagia; psychomotor activity; Hypersomnia; masturbation; Hyper-sexuality; Kleine-Levin syndrome