Citation

Nakajima T. Osaka-shi Igakkai Zasshi 2012; 61(1-2): 21-26.

Copyright

(Copyright © 2012, Osaka City Medical Center)

DOI

unavailable

PMID

unavailable

Abstract

[Objective] The aim of the current study was to elucidate the differences in clinical features of female eating disorder patients with and without comorbid obsessive compulsive disorder (OCD). [Methods] Subjects consisted of 279 female patients with eating disorder who were referred to the Department of Neuropsychiatry, Osaka City University Hospitals between April 1999 and April 2007. All subjects underwent semi-structured interviews including the Structured Clinical Interview for DSM-IV (SCID-I) and the Structured Clinical Interview for DSM-IV Personality Disorders (SCID-II) to assess other psychiatric disorders, Global Assessment of Functioning Scale (GAF) scores, personality disorders, and impulsive behaviors such as suicide attempt, self-mutilation, shoplifting and sexual promiscuity. Clinical features and psychiatric comorbidity of the eating disorder patients with and without OCD were compared. [Results] Twenty-three (8.2%) subjects had lifetime diagnosis of OCD. The patients with OCD showed significantly lower GAF scores, and were significantly more likely to have comorbid major depressive disorder, dysthymic disorders, agoraphobia, social anxiety disorders, and history of suicidal attempts compared with those without OCD. Ninety-six Percent of the patients with OCD had either of major depressive disorder or dysthymic disorders. In logistic regression analysis with stepwise variable selection, major depressive disorder, dysthymic disorders, and GAF scores were selected as the factors related to OCD. [Conclusions] The comorbidity of OCD among female patients with eating disorders was related to high comorbidity of mood disorder such as major depressive disorder or dysthymic disorders, and lower social functioning. Therefore, it is important to diagnose comorbid OCD in order to develop treatment strategies for eating disorder patients.

Language: ja

Keywords

human; female; suicide attempt; major depression; comorbidity; article; major clinical study; eating disorder; controlled study; dysthymia; psychologic assessment; clinical feature; automutilation; social phobia; obsessive compulsive disorder; agoraphobia; Structured Clinical Interview for DSM Disorders; sexual promiscuity