Citation

Attard A. Medicine (Abingdon) 2012; 40(12): 681-683.

Copyright

(Copyright © 2012, Medicine Publishing)

DOI

10.1016/j.mpmed.2012.09.007

PMID

unavailable

Abstract

Many types of antidepressant are available. They vary in mode of action and adverse effect profile. The groups of antidepressants are presented together with their mode of action, drug interactions, adverse effects and their use in vulnerable patient groups. This article further discusses briefly the issues of suicide risk, antidepressant time to effect, first-line antidepressant choice and treatment of treatment-resistant depression. Issues faced when switching between antidepressants and symptoms of antidepressant discontinuation syndrome are also highlighted. © 2012 Elsevier Ltd. All rights reserved.

Language: en

Keywords

human; suicide; alcohol; insomnia; abdominal pain; depression; schizophrenia; risk assessment; antidepressants; review; fatigue; anorexia; vomiting; antidepressant agent; sexual dysfunction; amfebutamone; drug induced disease; fluoxetine; fluvoxamine; mirtazapine; monoamine oxidase inhibitor; serotonin uptake inhibitor; sertraline; tachycardia; tricyclic antidepressant agent; venlafaxine; xerostomia; priority journal; headache; somnolence; bleeding; anxiety disorder; urine retention; drowsiness; constipation; drug mechanism; orthostatic hypotension; reboxetine; appetite; edema; drug safety; backache; trazodone; drug efficacy; diarrhea; nausea; tremor; leukopenia; sweating; side effect; cimetidine; duloxetine; agitation; flu like syndrome; liver toxicity; body weight; hyponatremia; buspirone; paresthesia; nervousness; dyspepsia; dizziness; drug eruption; Hypericum perforatum extract; muscarinic receptor blocking agent; SSRIs; skin disease; TCAs; hyperhidrosis; blurred vision; hangover; sensory dysfunction; agomelatine; antidepressant discontinuation syndrome; cutaneous bleeding disorder; D; discontinuation syndrome; MAOIs; refractory schizophrenia; STAR; treatment resistant depression