Citation

Liu JL, Yuan YH, Chen NH. Chinese Pharmacological Bulletin 2011; 27(9): 1193-1196.

Copyright

(Copyright © 2011)

DOI

10.3969/j.issn.1001-1978.2011.09.003

PMID

unavailable

Abstract

Depression is characteristic with sustained depressive mood and cognitive dysfunction in the clinic, including restlessness , anhedoina, sleep disorders, guilt and repeated thoughts of suicide and so on. Depression not only damages the mentality of patients, bu also brings a heavy financial burden to patients. Based on the depression-related hypothesis: the monoamine hy-pothesis, stress hypothesis, neurotrophic factors and neurogenesis hypotheses etc., and from different mechanisms and signal pathwas, we reviewed the progress of the treatment of depression.

Language: zh

Keywords

Depression; depression; review; medical research; psychiatric treatment; hypothesis; Drug therapy; Mechanism; neurotrophic factor; monoamine hypothesis; neurogenesis hypothesis; Neurotization; Neurotrophic factors; Receptors; stress hypothesis