Citation

Kobayashi T, Saito N, Suda S, Shioda K, Kato S. Pharmacopsychiatry 2011; 44(7): 346-347.

Copyright

(Copyright © 2011, Georg Thieme Verlag)

DOI

10.1055/s-0031-1284429

PMID

unavailable

Abstract

A case of pharmacoresistant convulsions after selegiline overdose is reported. A 50-year-old male having been suffering from bipolar II disorder for 16 years attempted suicide by taking an overdose of 195 mg selegiline with other psychotropics. He developed recurrent pharmacoresistant seizure from 12 th day to 19th day after selegiline overdose. He also had visual hallucinations and temporary high blood pressure. The authors suspect that the catecholamine-influenced convulsions and visual hallucinations that manifested during the period increased by the MAO-inhibiting action of selegiline which lasts about 2 weeks. © Georg Thieme Verlag KG Stuttgart · New York.

Language: en

Keywords

Humans; Male; Middle Aged; adult; human; male; Drug Overdose; Seizures; Suicide, Attempted; case report; bipolar disorder; depression; suicide attempt; complication; Phenytoin; overdose; drug overdose; Monoamine Oxidase Inhibitors; article; anticonvulsive agent; monoamine oxidase inhibitor; selegiline; priority journal; middle aged; coma; myoclonus; diazepam; nitrazepam; confusion; convulsion; Bipolar Disorder; trazodone; carbamazepine; valproic acid; hypnotic agent; phenytoin; antibiotic agent; aspiration pneumonia; Anticonvulsants; Coma; drug resistance; antibiotic therapy; mood stabilizer; add on therapy; extubation; Diazepam; Drug Resistance; Hallucinations; visual hallucination; chemically induced; grand mal seizure; Selegiline