Citation

Bakhshayeshkaram M, Saidi B, Tabarsi P, Zahirifard S, Ghofrani M. Iran J. Radiol. 2011; 8(4): 230-234.

Copyright

(Copyright © 2011, Teheran University of Medical Sciences ; Iranian Radiological Society)

DOI

10.5812/iranjradiol.4554

PMID

unavailable

Abstract

Background Swine influenza (H1N1) is a very contagious respiratory infection and World Health Organization (WHO) has raised the alert level to phase 6 (pandemic). The study of clinical and laboratory manifestations as well as radiologic imaging findings helps in its early diagnosis.

OBJECTIVEs The aim of this study was to evaluate the imaging findings of patients with documented H1N1 infection referred to our center. Patients and Methods Thirty-one patients (16 men) with documented H1N1 infection were included in our study. The initial radiography obtained from the patients was reviewed regarding pattern (consolidation, ground glass, nodules and reticulation), distribution (focal, multifocal, and diffuse) and the lung zones involved. Computed tomography (CT) scans were also reviewed for the same abnormalities. The patient files were studied for their possible underlying diseases.

RESULTS The mean age was 37.97 ± 13.9 years. Seventeen (54.8%) patients had co-existing condition (eight respiratory, five cardiovascular, two immunodeficiency, two cancer, four others). Twelve (38.7%) patients required intensive care unit (ICU) admission. Five (16.1%) patients died. (25.8%) had normal initial radiographs. The most common abnormality was consolidation (12/31; 38.7%) in the peripheral region (11/31; 35.5%) followed by peribronchovascular areas (10/31; 32.3%) which was most commonly observed in the lower zone. The patients admitted to the ICU were more likely to have two or more lung zones involved (P = 0.005).

CONCLUSIONS In patients with the novel swine flu infection, the most common radiographic abnormality observed was consolidation in the lower lung zones. Patients admitted to ICU were more likely to have two or more lung zones involved. © 2011, Tehran University of Medical Sciences and Iranian Society of Radiology.

Language: en

Keywords

adult; human; suicide; female; male; ischemic heart disease; Iran; aged; image analysis; addiction; controlled study; clinical article; Human immunodeficiency virus infection; intensive care unit; convulsion; asthma; computer assisted tomography; hypertension; creatine kinase; chronic obstructive lung disease; leukocyte count; Infection; radiography; lactate dehydrogenase; Article; hemoglobin; immune deficiency; thrombocyte count; lymphadenopathy; multiple myeloma; pleura effusion; influenza A (H1N1); H1N1 Subtype; Influenza A Virus; joint cancer; pleura thickening; Radiography; Thoracic; Tomography; X-Ray Computed