Citation

Patil VC, Patil HV, Sakaria A. Med. Legal Update 2011; 11(2): 112-113.

Copyright

(Copyright © 2011, R.K. Sharma and Institute of Medico-Legal Publications)

DOI

unavailable

PMID

unavailable

Abstract

Phenobarbital is long acting barbiturate with low lipid solubility that act as central nervous system depressants and used as anticonvulsant, sedative, hypnotic drug. In acute severe barbiturate intoxication, through CNS depression, coma, respiratory arrest and hypotension may occur, which are the major causes of mortality. Mortality is high for blood levels over 80 micro/mL and the lethal dose in adult is estimated as 6 to 10 gram. We report a case of Phenobarbital intoxication in a 24 years old female, with history of consumption of 120 tablets of phenobarbitone of 60 milligram each (7.2 gram) who was successfully treated by emergency charcoal hemoperfusion.

Language: en

Keywords

adult; human; suicide; female; hypothermia; shock; case report; intoxication; article; stomach lavage; catheterization; activated carbon; fluid therapy; intensive care; hypotension; artificial ventilation; phenobarbital; antibiotic agent; electrocardiogram; diuresis; respiration depression; blood pressure; thorax radiography; oxygen therapy; hemoperfusion; intubation; comatose patient; hospital infection; medical history; respiratory acidosis; pulse rate; Charcoal haemoperfusion; Cheyne Stokes breathing; lung insufficiency; phenobarbital intoxication; Phenobarbital poisoning