Citation

Sinjan E, Rutsaert R, Druwe P. Tijdschrift voor Geneeskunde 2010; 66(17): 826-829.

Copyright

(Copyright © 2010)

DOI

10.2143/TVG.66.17.2000817

PMID

unavailable

Abstract

For more than twenty years hair dye poisoning by intentional paraphenylene-diamine (PPD) ingestion has been a common and potentially severe way of suicide in Northern Africa, the Indian subcontinent and Saudi Arabia. We report the case of a 37-year-old Moroccan woman who committed suicide by deliberate ingestion of PPD. Systemic toxicity of PPD is characterized by acute respiratory distress secondary to laryngeal edema, rhabdomyolysis with myoglobinuria and a chocolate brown colored urine as well as acute renal failure. Myocardial injury may be a fatal complication. No specific antidote exists against PPD, the treatment remaining supportive. Mortality rate is high.

Language: nl

Keywords

adult; human; suicide; female; case report; rhabdomyolysis; intoxication; article; larynx edema; heart muscle injury; respiratory distress; outcome assessment; hair dye; n,n,n',n' tetramethyl 1,4 phenylenediamine; urine composition disorder