Citation

Kavalci C, Guldiken S, Taskiran B. Internet Journal of Internal Medicine 2010; 8(1).

Copyright

(Copyright © 2010)

DOI

unavailable

PMID

unavailable

Abstract

A 55 year-old male patient was admitted to emergency department. He ingested 50-60 tablets of 850 mg metformin for suicidal attempt. Blood glucose 352 mg/dL, ALT 52 IU/L, AST 39 IU/L, LDH 441 IU/L, lactate over 181 mg/dL, pH 7.29, pO2 44 mmHg, pCO2 39 mmHg, HCO3 18 mEq/L, oxygen saturation was 74%. Bicarbonate was given by intravenous push at a dose of 1 mEq/kg body weight and the patient was transferred to the intensive care unit. Haemofiltration was performed for lactic acidosis. As a result, haemofiltration should be initiated immediately in patients with acidosis associated with metformin. Thus mortality rates can be lessened. © Internet Scientific Publications, LLC., 1996 to 2010.

Language: en

Keywords

adult; human; male; resuscitation; case report; abdominal pain; suicide attempt; drug overdose; Lactic acidosis; Metformin; clinical feature; somnolence; letter; pH; nausea; hypotension; heart arrest; glucose blood level; alanine aminotransferase; aspartate aminotransferase; glucose; bicarbonate; electrocardiogram; hemofiltration; leukocyte count; non insulin dependent diabetes mellitus; charcoal; respiratory arrest; lactate dehydrogenase; glipizide; lactic acidosis; metformin; oxygen saturation; Emergency; hemoglobin; rosiglitazone; hematocrit; lactic acid; sinus rhythm