Citation

Wong OF, Fung HT, Lam T. Hong Kong J. Emerg. Med. 2010; 17(3): 276-280.

Copyright

(Copyright © 2010, Medcom Limited)

DOI

10.1177/102490791001700314

PMID

unavailable

Abstract

Bezoar formation is cited to be the cause of delayed absorption of aspirin in overdose of enteric-coated aspirin preparation. However, such phenomenon from oral overdose of regular aspirin preparation has not been clearly demonstrated in human. The use of multiple-dose activated charcoal (MDAC) in salicylate poisoning remains controversial. We report a case of regular-preparation salicylate poisoning with rebound of the serum salicylate level after discontinuation of MDAC administration. Bezoar formation as the underlying cause of the rebound and the effect of MDAC on serum salicylate level are discussed.

Language: en

Keywords

adult; human; male; Poisoning; case report; Overdose; suicide attempt; drug overdose; Aspirin; alcohol consumption; article; acetylsalicylic acid; activated carbon; drug blood level; nausea; hypertension; epigastric pain; tinnitus; bicarbonate; potassium; potassium blood level; alkalinization; urine; international normalized ratio; blood examination; Salicylates; bezoar; Bezoars; beer; multiple cycle treatment; urine pH; multiple drug dose