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Citation |
Isidro ML, Cordido F. Pharmaceuticals (Basel) 2010; 3(1): 125-145. |
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Copyright |
(Copyright © 2010, MDPI) |
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DOI |
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PMID |
unavailable |
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Abstract |
Available anti-obesity pharmacotherapy options remain very limited and development of more effective drugs has become a priority. The potential strategies to achieve weight loss are to reduce energy intake by stimulating anorexigenic signals or by blocking orexigenic signals, and to increase energy expenditure. This review will focus on approved obesity medications, as well as potential new pharmacologic treatment options. © 2010 by the authors. Language: en |
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Keywords |
human; suicide; insomnia; abdominal pain; depression; food intake; clinical trial; Obesity; review; obesity; mental disease; tachycardia; unclassified drug; anxiety disorder; drug mechanism; gastrointestinal symptom; energy expenditure; nonhuman; drug safety; placebo; food and drug administration; drug dependence; drug efficacy; diarrhea; drug tolerability; nausea; drug withdrawal; restlessness; beta adrenergic receptor stimulating agent; unindexed drug; hypertension; side effect; leptin; serotonin agonist; cardiovascular symptom; drug approval; flatulence; non insulin dependent diabetes mellitus; drug potency; feces incontinence; blood pressure; dizziness; treatment contraindication; drug bioavailability; kinesiotherapy; dyslipidemia; tetrahydrolipstatin; Ghrelin; diet therapy; sibutramine; satiety; spotting; off label drug use; lifestyle modification; drug stability; (3 chlorophenyl)piperazine; rimonabant; hormone receptor stimulating agent; oxyntomodulin; peptide YY; recombinant ciliary neurotrophic factor; Sibutramine; Leptin; phentermine; Rimonabant; drug degradation; lorcaserin; Orlistat; Drug treatment; abnormal feces; bvt 74316; defecation urgency; gastrointestinal polypeptide; ghrelin receptor agonist; glucagon like peptide 1 receptor agonist; growth hormone receptor agonist; leptin receptor agonist; melanin concentrating hormone receptor 1 antagonist; melanocortin receptor agonist; neuropeptide Y receptor antagonist; proopiomelanocortin; prx 07034; recombinant growth hormone; ro 27 3225; serotonin 6 antagonist; somatostatin derivative |