Citation

Amen DG, Prunella JR, Fallon JH, Amen B, Hanks C. J. Neuropsychiatry Clin. Neurosci. 2009; 21(4): 430-439.

Copyright

(Copyright © 2009, American Neuropsychiatric Association, Publisher American Psychiatric Publishing)

DOI

10.1176/jnp.2009.21.4.430

PMID

unavailable

Abstract

The authors compared regional cerebral blood flow in the brains of 12 psychiatric patients who completed the act of suicide with groups of healthy and nonsuicidal depressed subjects using statistical parametric mapping.

RESULTS were consistent with prior imaging studies on depression and were indicative of impaired impulse control and limbic dysregulation, including significant perfusion deficits in the medial prefrontal and subgenual areas (Brodmann's areas 11, 25) and ventral tegmentum. These results warrant further research. Copyright © 2009 American Psychiatric Publishing, Inc.

Language: en

Keywords

adult; human; suicide; female; male; depression; prefrontal cortex; article; major clinical study; controlled study; priority journal; impulse control disorder; brain blood flow; brain region; single photon emission computer tomography; brain perfusion; parametric test; ventral tegmentum