Citation

Bergemann N. J. Neurol. Neuroch. Psychiatr. 2009; 10(1): 41-47.

Copyright

(Copyright © 2009, Krause & Pachernegg)

DOI

unavailable

PMID

unavailable

Abstract

Depressive disorders not only develop in childbed as postnatal depression; they also occur frequently during pregnancy. Indeed, the incidence in the second and third trimesters of pregnancy was found in a recently published meta-analysis to be 12.8 % and 12.0 %, respectively. Therefore, treatment with antidepressants is often required. The overview presented here shows that numerous antidepressants are only associated with a relatively low risk of complications and can also be administered during pregnancy. However, the risks and benefits of prescribing antidepressants must be weighed against any possible hazards for the child with respect to the drug's effects on reproduction or its fetotoxic properties and the risk for mother and child if a depressive disorder is not treated as this can result in nutrition deficiencies or even suicide.

Language: de

Keywords

human; suicide; depression; drug use; pregnancy; review; mother; risk; prescription; doxepin; amfebutamone; amitriptyline; citalopram; clomipramine; desipramine; fluoxetine; fluvoxamine; imipramine; mirtazapine; moclobemide; nortriptyline; paroxetine; sertraline; tricyclic antidepressant agent; trimipramine; venlafaxine; hazard; psychopharmacology; reproduction; reboxetine; mianserin; tranylcypromine; nonhuman; nutritional deficiency; maprotiline; drug effect; duloxetine; escitalopram; amitriptylinoxide; opipramol; fetotoxicity