Citation

Drtílková I. Ceska Slov. Psychiatr. 2007; 103(1): 22-27.

Copyright

(Copyright © 2007, Ceska Lekarska Spolecnost Jana Evangelisty Purkyne)

DOI

unavailable

PMID

unavailable

Abstract

A small minority of children and adolescents (2-3%) seems prone to suicidality when defined as increased suicidal ideation or behavior during treatment with antidepressants.. Mechanisms proposed to explain emergence of suicidality during antidepressant treatment are : progression of underlying depression reflecting ineffective treatmnent, energizing phenomen, activation syndrome and stage shift from depression into mania or mixed state.Future studie of clinical or biological markers may allow a better prediction of which pediatric patiens are most liable to show behavioral sensitivity to antidepressants.

Language: cs

Keywords

human; Risk; Children; suicidal ideation; depression; Suicidality; Antidepressants; suicidal behavior; clinical trial; risk factor; article; antidepressant agent; amfebutamone; citalopram; fluoxetine; mirtazapine; nefazodone; serotonin uptake inhibitor; sertraline; venlafaxine; disease course; placebo; mania; treatment failure; mixed mania and depression; serotonin noradrenalin reuptake inhibitor