Citation

Şahin Yildiz T, Hoşten T, Toker K, Solak M. Anestezi Dergisi 2006; 14(3): 210-212.

Copyright

(Copyright © 2006, Anesteziyoloji ve Reanimasyon Uzmanları Derneği)

DOI

unavailable

PMID

unavailable

Abstract

Because of the narrow therapeutic index of lithium and the increasing number of patients on long-term therapy, toxicity is becoming more common. A 50-year-old woman was admitted to the intensive care unit after taking an intentional overdose of lithium tablets, mianserin hydrochloride, biperiden hydrochloride, and alprazolam in a suicide attempt and being intubated. The serum lithium level of the patient, who had previously been treated with lithium for 10 years due to a bipolar affective disorder, was 8.30 mEq L-1 on admission. The patient was treated by forced diuresis, continuous venovenous hemodiafiltration (CVVHDF) followed by hemodialysis. On the seventeenth day in the intensive care unit, the lithium level was 0.2 mEq L-1. She was discharged to the psychiatric ward in a fully conscious and cooperative state on the thirty-ninth day of intensive care. In this case report, we aimed to evaluate our practice on a patient with life-threatening acute lithium intoxication, who was treated successfully with forced diuresis and CVVHDF followed by hemodialysis.

Language: tr

Keywords

adult; Intoxication; human; female; case report; bipolar disorder; Hemodialysis; hemodialysis; suicide attempt; lithium; Lithium; treatment outcome; drug overdose; article; clinical practice; drug intoxication; hospital admission; intensive care unit; alprazolam; mianserin; drug blood level; intensive care; hospital discharge; biperiden; consciousness; diuresis; respiratory tract intubation; treatment duration; Acute; continuous hemodiafiltration; Hemodiafiltration