Citation

Ford JD. Psychiatr. Ann. 2005; 35(5): 410-419.

Copyright

(Copyright © 2005, Healio)

DOI

10.3928/00485713-20050501-07

PMID

unavailable

Abstract

Research is needed to further deconstruct and define the neurobiological substrates of specific components of self-regulation in relation to early childhood trauma-related PTSD. Brain activation patterns related to dissociation have been investigated preliminarily21,31 and similar studies are needed to provide greater specificity than that provided by categorical diagnoses (eg, PTSD). Self-regulation can provide a basis for theoretical models and interventions that focus on posttraumatic resilience.31 Future success in developing effective treatments for children and adults who experience complex biopsychosocial impairments following exposure to early life DAIT depends upon continued dialogue between scientists and clinicians who share a focus on the nature, neurobiology, and development of affective and cognitive self-regulation.

Language: en

Keywords

human; child abuse; depression; central nervous system; prefrontal cortex; psychosis; suicide attempt; Diagnostic and Statistical Manual of Mental Disorders; posttraumatic stress disorder; dissociative disorder; mood disorder; neuroimaging; conduct disorder; emotional disorder; substance abuse; article; eating disorder; disease classification; personality disorder; hydrocortisone; cognitive defect; anxiety disorder; information processing; neurobiology; hypothalamus hypophysis adrenal system; diabetes mellitus; heart disease; brain function; corticotropin; sleep waking cycle; brain region; brain stem; mental task; frontal cortex; amygdaloid nucleus; corpus callosum; immune deficiency; working memory