Citation

Bronisch T. Krankenhauspsychiatrie, Supplement 2005; 16(1): S27-S33.

Copyright

(Copyright © 2005)

DOI

10.1055/s-2005-870990

PMID

unavailable

Abstract

The antisuicidal pharmacological treatment comprises antidepressants, neuroleptics, lithium, and mood stabilizers. Lithium seems to have at the moment the best empirical results in treatment of suicidality, whereas a weak, moderate or strong efficacy is postulated for antidepressants. Indirect studies (post-mortem, psychological autopsy, epidemiological, and intervention studies) give indicators for a strong efficacy of antidepressants. Data are not sufficient for evaluating the antisuicidal properties of neuroleptics and mood stabilizers. In summary, there is an urgent need for, if possible prospective placebo controlled studies of acute or chronic unipolar and bipolar depressives. © Georg Thieme Verlag Stuttgart.

Language: de

Keywords

human; Depression; suicide; Suicide; autopsy; bipolar disorder; Suicide attempt; major depression; lithium; disease severity; Pharmacotherapy; review; antidepressant agent; disease association; neuroleptic agent; statistical analysis; amitriptyline; fluoxetine; paroxetine; serotonin uptake inhibitor; mental health service; statistical significance; flupentixol; mianserin; carbamazepine; drug efficacy; valproic acid; maintenance therapy; drug response; mood stabilizer