Citation

Dong X, Shovestul B, Saxena A, Dudek E, Reda S, Lamberti JS, Dodell-Feder D. Schizophr. Res. Cogn. 2024; 37: e100314.

Copyright

(Copyright © 2024, Elsevier Publishing)

DOI

10.1016/j.scog.2024.100314

PMID

38764743

PMCID

PMC11101893

Abstract

Schizophrenia spectrum disorders (SSD) are associated with pervasive cognitive impairments, including deficits in decision-making under risk. However, there is inconclusive evidence regarding specific mechanisms underlying altered decision-making patterns. In this study, participants (33 SSD and 28 non-SSD) completed the Columbia Card Task, an explicit risk-taking task, to better understand risk preference and adjustment in dynamic decision-making. We found that while there is no group difference in overall risk-taking, risk preference, or optimal decision-making, risk adjustment to contextual factors (e.g., loss probability) is blunted in SSD. We also found associations between risk-taking/suboptimal decision-making and disorganized symptoms, excited symptoms, and role functioning, but no associations between decision-making and working memory. These results suggest that during a complex, dynamic risk-taking task, individuals with SSD exhibit less adaption to changing information about risk, which may reflect risk imperception.

Language: en

Keywords

Columbia Card Task; Decision-making; Psychosis; Risk; Risk imperception; Schizophrenia